With a few exceptions, every USB communication is between a host and a device. The host contains hardware and programming for accessing devices, and the the device contains hardware and programming for communicating with the host.
On power up or attachment, the device sends a series of data structures called descriptors that specify what USB class or vendor driver the host must support if it wants to communicate.
Windows Device Manager will tell you what driver the guitar is using. If the interface appears as a serial (COM) port, Windows is using a USB virtual serial port driver. Otherwise, check the Driver entry for the device.
If you want to replace the guitar's USB interface with Bluetooth, a USB/Bluetooth adapter will give you Bluetooth on the PC.
But the guitar's USB interface is expecting to attach to a USB host. So you will need to develop an adapter that contains (1) USB host hardware and programming for communicating with the guitar's USB device port, (2) a Bluetooth interface that can communicate with the PC's Bluetooth port, and (3) programming inside the adapter to send received USB data to the Bluetooth port and send received Bluetooth data to the USB port.
If the guitar already has a Bluetooth interface, or a serial port, or if you are developing the guitar and can add a Bluetooth interface directly, you won't have to do the USB conversion.
For more about USB hosts in small devices, see:
http://janaxelson.com/embedded_host.htm