It is hard to tell if your question is actually
"How can I distinguish my devices from each other because they are the same?"
or
"How do I keep track of multiple devices attached to one computer?"
Of course, Jan answered both.
If it is the first question, then you need to make them different, eg with serial numbers, or PIDs, or something you can query.
The devices show up differently depending on where they are in your USB topology and once you get a handle to one of them, that handle will always be for that same device. (This is why Windows "reinstalls" your device each time you change the topology--eg plug it into a different port.)